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Purchase generic accutane (Accutane) and the first new type of medication to have a generic drug approved for this indication (purchase generic brentuximab (Vemur/Sargram/Wyeth) and the first new non-Hodgkin lymphoma drug buy generic accutane 40 mg to have a generic in the American regulatory system ). Although this trend of generic drug innovation represents progress, it does not come without controversy, as many studies indicate that generic drugs are typically more expensive than brand name pharmaceuticals. As most physicians have been trained to believe that generic drugs are Buy cheap zyprexa online often safer than brand name drugs, the potential adverse effects of generic drugs have been underestimated . In light of this, the purpose this study was to compare safety and tolerability of two different, clinically similar, short-term pharmacological treatments for MS with two brand-name long-term therapies (Ritalin and Prozac). The first pharmacological treatment was a new, short-acting medication developed by Vemur Corporation, Inc. (Vemur) that was recently approved by the Food and Drug Administration (FDA) on June 2, 2005 (; Figure 1). The medication, Vemur (imatinib/lamivudine) is a bivalent, nonsteroidal, alpha-1 antitrypsin-like proteinase inhibitor. It has been shown in human and animal studies to be safe and well-tolerated, has recently been used in clinical trials for the treatment of multiple sclerosis patients. The same month that Vemur was approved by the FDA, Prozac was approved by the FDA, and is a selective serotonin reuptake inhibitor of the type (SSRI; serotonin and norepinephrine reuptake inhibitor) . This medication was approved by the FDA in 1990 for treatment of depression, and has been shown to have safe and well-tolerated effects in patients. Figure 1. Table Summary of Treatment Approvals New Generic Medications for Multiple Sclerosis by Year of Approval (FDA, 2005). Drugs are listed alphabetically; no significant differences were observed from 2001. Vemur is a new, short-acting medication that works by selectively removing a specific amino acid from the body. In addition to its effect on MS, it appears to be effective in certain other indications such as high fevers, irritability, and sleep disturbances in patients with diabetes . the present study, which is first-ever placebo-controlled, dose-ranging, double-blind clinical trial for Vemur, 11% (12%) of patients were randomized to receive Vemur and 16% (17%) of patients were randomized to Prozac, which has been approved by the FDA for treatment of depression in 2002. All Vemur patients and Prozac were asked to discontinue all medications except Vemur at entry (baseline). The two drugs were then given buy accutane online canada in an identical fashion and similar amounts. Safety was measured by a series of questionnaires completed by all patients 3 weeks after the study was stopped. 10 weeks of continued drug treatment, the two treatment arms were continued until the end of study, or until the patient discontinued drugs due to side effects. In the placebo group (n = 8), no patient was assigned to receive Vemur as placebo, and the patient was instructed to discontinue all medications and return for a check 2 weeks after the follow-up check. Although we cannot make any statements regarding safety and efficacy from these studies, studies can provide some general insight into the safety of Vemur. These data do not necessarily indicate that purchase generic accutane Vemur is safe and will not cause side effects, rather they reflect two different drug designs and protocols; however, the two sets of trials suggest that both drug types may have a similar safety profile. At week 10 of this study, 8 (16%) the Vemur patients developed high blood pressure, a condition that has been the primary side effect of Vemur and other bivalent alpha-1-antitrypsin (PAS) Top 10 drugstore primers uk inhibitors. Only one patient (1%) of the Prozac group developed high blood pressure. Although the Vemur and Prozac group was comparable in treatment arm assignments, as shown in Table 1, there were no significant differences between them in the average dose of Vemur or Prozac per day. It was possible that the Prozac administration was slightly less intense; however, this effect is highly unlikely to explain the difference in observed incidence of high blood pressure between Vemur and Prozac. No patient reported any side effects on Vemur from these three doses or longer, and none of the Prozac subjects reported any side effects. It should be noted, however, that it can be difficult to distinguish between the effects of a drug or effect placebo. Thus, it will be of interest to know whether there are.